Skupina genové regulace

Ing. Tomáš Vacík, Ph.D.

email: tomas.vacik@lf1.cuni.cz

tel.: +420 224 968 015

Our research is focused on elucidating the molecular mechanisms behind various cellular processes involved in transcriptional regulation, epigenetics and chromatin structure. We are using mainly molecular biology methods and in silico approaches to study the function of various nuclear chromatin regulating proteins and of their frequently overlooked alternative isoforms. Since misregulation of various alternative intronic promoters is known to be associated with developmental defects and human diseases, we are interested in finding out more about transcriptional regulation of selected intronic promoters and about the consequences of their misregulation.

PhD position available. If you are interested, please send an email to tomas.vacik@lf1.cuni.cz.